Ccl6 Gene Summary [Rat]
Enables chemokine activity. Involved in cell chemotaxis. Predicted to be active in extracellular space. Orthologous to several human genes including CCL15 (C-C motif chemokine ligand 15) and CCL23 (C-C motif chemokine ligand 23). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ccl6 |
| Official Name | chemokine (C-C motif) ligand 6 [Source:RGD Symbol;Acc:1303200] |
| Ensembl ID | ENSRNOG00000030021 |
| Bio databases IDs | |
| Aliases | chemokine (C-C motif) ligand 6 |
| Synonyms | c10, C-C motif chemokine ligand 6, MRP-1, Scay6, Scya6 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Ccl6 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- CCR chemokine receptor binding
- chemokine
- chemoattractant
- Small cytokines (intecrine/chemokine), interleukin-8 like
- cytokine
Pathways
Biological processes and signaling networks where the Ccl6 gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- rheumatoid arthritis
- insulin-dependent diabetes mellitus
- plasma cell neoplasm
- B cell cancer
- mature B-cell neoplasia
- amyloidosis
role in cell
- apoptosis
- formation
- growth
- activation
- recruitment
- migration
- chemotaxis
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- cell surface
- intracellular space