Cpsf1 Gene Summary [Rat]
Predicted to enable enzyme binding activity and mRNA 3'-UTR AU-rich region binding activity. Predicted to be located in nucleoplasm. Predicted to be part of mRNA cleavage and polyadenylation specificity factor complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in myopia. Orthologous to human CPSF1 (cleavage and polyadenylation specific factor 1). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Cpsf1 |
| Official Name | cleavage and polyadenylation specific factor 1 [Source:RGD Symbol;Acc:1306406] |
| Ensembl ID | ENSRNOG00000030705 |
| Bio databases IDs | |
| Aliases | cleavage and polyadenylation specific factor 1 |
| Synonyms | cleavage and polyadenylation specific factor 1, CPSF160, Cpsf 160 kDa Subunit, HSU37012, MYP27, P/cl.18 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Cpsf1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- mRNA 3' UTR binding
- Mono-functional DNA-alkylating methyl methanesulfonate N-term
- enzyme binding
- protein binding
- CPSF A subunit region
Pathways
Biological processes and signaling networks where the Cpsf1 gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoplasm
- interchromatin granule clusters
- plasma
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Cpsf1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- mRNA processing
Cellular Component
Where in the cell the gene product is active
- nucleus
- mRNA cleavage and polyadenylation specificity factor complex
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- mRNA 3'-UTR AU-rich region binding
- enzyme binding