Dpp3 Gene Summary [Rat]
Enables zinc ion binding activity. Involved in protein catabolic process. Predicted to be located in cytosol. Predicted to be active in cytoplasm. Orthologous to human DPP3 (dipeptidyl peptidase 3). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Dpp3 |
| Official Name | dipeptidylpeptidase 3 [Source:RGD Symbol;Acc:621127] |
| Ensembl ID | ENSRNOG00000031485 |
| Bio databases IDs | |
| Aliases | dipeptidylpeptidase 3 |
| Synonyms | 4930533O14Rik, dipeptidyl peptidase 3, DPP III |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Dpp3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- zinc ion binding
- peptidase
- dipeptidyl-peptidase III
- Peptidase family M49
- ETGE motif
- dipeptidyl-peptidase
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- neoplasia
- diastolic dysfunction
- hepatocellular carcinoma
- liver cancer
- epithelial cancer
- organismal death
- cardiac fibrosis
- lung squamous cell carcinoma
- squamous cell lung cancer
- colorectal cancer
role in cell
- expression in
- cellular infiltration by
- proliferation
- cell viability
- apoptosis
- migration
- activation in
- colony formation by
- number
- binding in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Dpp3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein catabolic process
- proteolysis
Cellular Component
Where in the cell the gene product is active
- extracellular vesicular exosome
- cytoplasm
- cytosol
Molecular Function
What the gene product does at the molecular level
- zinc ion binding
- protein binding
- metalloexopeptidase activity
- aminopeptidase activity
- dipeptidyl-peptidase activity