Mrpl52 Gene Summary [Rat]

Predicted to be located in mitochondrion and nucleoplasm. Predicted to be part of mitochondrial large ribosomal subunit. Orthologous to human MRPL52 (mitochondrial ribosomal protein L52). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Mrpl52
Official Name
mitochondrial ribosomal protein L52 [Source:RGD Symbol;Acc:1309297]
Ensembl ID
ENSRNOG00000039297
Bio databases IDs NCBI: 361037 Ensembl: ENSRNOG00000039297
Aliases mitochondrial ribosomal protein L52
Synonyms 1110047B07Rik, mitochondrial ribosomal protein L52, mL52
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Mrpl52 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • structural constituent of ribosome
  • Mitoribosomal protein mL52
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • breast cancer
regulated by
  • HIF1A
  • beta-estradiol
  • ESR1
  • WWTR1
  • estradiol-17beta-benzoate
  • megakaryocytes
regulates
role in cell
  • expression in
  • invasion by
  • migration
  • apoptosis
  • cell viability
  • transmembrane potential
  • molecular cleavage in
  • opening in
  • epithelial-mesenchymal transition
  • mitophagy in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • ribosome
  • Mitochondria
  • mitochondrial inner membrane
  • nucleoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Mrpl52 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • mitochondrial translation
  • translation

Cellular Component

Where in the cell the gene product is active
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • mitochondrial inner membrane
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • structural constituent of ribosome

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.