Mrpl52 Gene Summary [Mouse]
Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Located in mitochondrion. Is expressed in several structures, including early conceptus; heart; liver; metanephros; and reproductive system. Orthologous to human MRPL52 (mitochondrial ribosomal protein L52). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Mrpl52 |
| Official Name | mitochondrial ribosomal protein L52 [Source:MGI Symbol;Acc:MGI:1916086] |
| Ensembl ID | ENSMUSG00000010406 |
| Bio databases IDs | |
| Aliases | mitochondrial ribosomal protein L52 |
| Synonyms | 1110047B07Rik, mitochondrial ribosomal protein L52, mL52 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Mrpl52 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- structural constituent of ribosome
- Mitoribosomal protein mL52
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- breast cancer
role in cell
- expression in
- invasion by
- migration
- apoptosis
- cell viability
- transmembrane potential
- molecular cleavage in
- opening in
- epithelial-mesenchymal transition
- mitophagy in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- ribosome
- Mitochondria
- mitochondrial inner membrane
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Mrpl52 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- mitochondrial translation
- translation
Cellular Component
Where in the cell the gene product is active
- mitochondrion
- mitochondrial large ribosomal subunit
- mitochondrial inner membrane
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- structural constituent of ribosome