Details
| Type | Protein Coding |
| Official Symbol | Fcgr2a |
| Official Name | Fc fragment of IgG receptor IIa [Source:RGD Symbol;Acc:71069] |
| Ensembl ID | ENSRNOG00000046663 |
| Bio databases IDs | |
| Aliases | Fc fragment of IgG receptor IIa |
| Synonyms | CD16, Cd32, Fc gamma 3R Alpha, Fc Gamma R3, Fc Gamma R3 Alpha, Fc gamma receptor 2A, Fc gamma receptor 2A like 1, Fc gamma receptor 2A, pseudogene 1, fc-gamma RIII, Fcgr2a, Fcgr2al1, Fcgr2a-ps1, Fcgr3a, Fc receptor, IgG, low affinity III, fcRIII, Fc γ 3R α, Fc γ R3, Fc γ R3 α, Fc γ receptor 2A, Fc γ receptor 2A like 1, Fc γ receptor 2A, pseudogene 1, fc-γ RIII, LOC100911825, LOC100912098, LOC103694909, LOC108348047 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Fcgr2a often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- IgG binding
- immunoglobulin domain
- Immunoglobulin like
- IgG receptor
- receptor binding
- transmembrane receptor
Pathways
Biological processes and signaling networks where the Fcgr2a gene in rat plays a role, providing insight into its function and relevance in health or disease.
- B Cell Receptor Signaling
- Dendritic Cell Maturation
- Fcγ Receptor-mediated Phagocytosis in Macrophages and Monocytes
- IL-10 Signaling
- IL-12 Signaling and Production in Macrophages
- Natural Killer Cell Signaling
- Parkinson's Signaling Pathway
- Phagosome Formation
- Role of NFAT in Regulation of the Immune Response
- Systemic Lupus Erythematosus Signaling
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- insulin-dependent diabetes mellitus
- hypersensitive reaction
- neoplasia
- hypersensitivity reaction type I
- adjuvant arthritis
- experimentally induced autoimmune hemolytic anemia
- hypersensitivity reaction type II
- experimental autoimmune encephalomyelitis
- bullous pemphigoid
- anaphylaxis
role in cell
- phosphorylation in
- expression in
- production in
- number
- quantity
- activation
- cytotoxic reaction
- antibody-dependent cell-mediated cytotoxic reaction
- adhesion
- degranulation
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cell surface
- cellular membrane
- plasma membrane extracellular face