Csf2ra Gene Summary [Rat]
Predicted to enable cytokine receptor activity. Involved in response to ethanol. Predicted to be part of granulocyte macrophage colony-stimulating factor receptor complex. Human ortholog(s) of this gene implicated in pulmonary alveolar proteinosis. Orthologous to human CSF2RA (colony stimulating factor 2 receptor subunit alpha). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Csf2ra |
| Official Name | colony stimulating factor 2 receptor alpha subunit [Source:RGD Symbol;Acc:1594330] |
| Ensembl ID | ENSRNOG00000049782 |
| Bio databases IDs | |
| Aliases | colony stimulating factor 2 receptor alpha subunit |
| Synonyms | CD116, colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage), colony stimulating factor 2 receptor subunit alpha, colony stimulating factor 2 receptor subunit α, colony stimulating factor 2 receptor, α, low-affinity (granulocyte-macrophage), Csfgmra, GM-CSFR, GM-CSF-Ra, GM-CSF receptor α |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Csf2ra often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- extracellular domain
- IL-3 receptor alpha chain N-terminal domain
- cytoplasmic domain
- FN3
- ectodomain
- proline rich domain
Pathways
Biological processes and signaling networks where the Csf2ra gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cell surface
- cellular membrane