Epdr1 Gene Summary [Rat]
Predicted to enable ganglioside GM1 binding activity; identical protein binding activity; and phospholipid binding activity. Predicted to be involved in myofibroblast contraction. Predicted to be located in extracellular region. Predicted to be active in lysosome. Orthologous to human EPDR1 (ependymin related 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Epdr1 |
| Official Name | ependymin related 1 [Source:RGD Symbol;Acc:1359161] |
| Ensembl ID | ENSRNOG00000060141 |
| Bio databases IDs | |
| Aliases | ependymin related 1 |
| Synonyms | AU040950, Epdm2, EPDR, Epdr2, ependymin related 1, EPENDYMIN RELATED protein 1, MERP-1, MERP-2, UCC1 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Epdr1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- phospholipid binding
- sphingolipid binding
- lipid binding
- binding protein
- Ependymin
- protein binding
- identical protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- cancer
- neoplasia
- epithelial cancer
- abdominal cancer
- epithelial neoplasia
- digestive system cancer
- liver cancer
- liver neoplasia
- Dupuytren contracture
- hepatocellular carcinoma
role in cell
- apoptosis
- expression in
- cell viability
- phosphorylation in
- ubiquitination in
- binding in
- migration
- invasion by
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Extracellular Space
- lysosome
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Epdr1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cell-matrix adhesion
Cellular Component
Where in the cell the gene product is active
- lysosomal lumen
- extracellular region
- lysosome
Molecular Function
What the gene product does at the molecular level
- identical protein binding
- protein binding
- calcium ion binding
- phospholipid binding