GeneGlobe ID: UPHS-039Z | Cat. No.: 249955 | QuantiNova LNA Probe PCR Focus Panels

QuantiNova LNA Probe PCR Focus Panel Human JAK / STAT Signaling Pathway

QuantiNova LNA Probe PCR Focus Panel
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Product Specification

Target List
JAK / STAT Signaling
Janus Kinases​
JAK1, JAK2, JAK3, TYK2
STAT Family Members​
STAT1, STAT2, STAT3, STAT4, STAT5A, STAT5B, STAT6
JAK / STAT Signaling Regulators​
PIAS1, PIAS2, PRL, PTPN1 (PTP1B), PTPRC, SOCS1, SOCS2, SOCS3, SOCS4, SOCS5
Cell Surface Receptors​
CSF1R, EGFR (ERBB1), EPOR, F2R (PAR1), GHR, IFNAR1, IFNGR1, IL10RA, IL2RA (CD25), IL2RG, IL4R (CD124), IL6ST (GP130), INSR, MPL, PDGFRA, SH2B1
SH3 / SH2 Adaptor Proteins​
CRK, GRB2, SRC, STAM
STAT-Interacting Transcription Factors & Regulators
Transcriptional Regulation​
HMGA1, SMAD3 (MADH3), SPI1
Transcription Factors​
JUNB, SP1, USF1
Transcriptional Coactivators & Corepressors​
JUNB, PIAS1, SMAD1 (MADH1), SMAD5 (MADH5), SP1, YY1
Other Transcription Factors & Regulators​
CEBPB, CRK, GATA3, IRF1, IRF9, JUN, MYC, NFKB1, NR3C1 (GRL), SMAD2 (MADH2), SMAD4 (MADH4)
STAT-Induced
STAT1-Induced​
CXCL9 (MIG), IRF1, JUNB, NOS2 (iNOS)
STAT3-Induced​
A2M, BCL2L1 (BCLXL), BCL2L1 (BCLXL), BCL2L1 (BCLXL), CCND1, CDKN1A (p21CIP1, WAF1), CEBPD, CRP, FAS, IRF1, LRG1, MCL1, MYC, SOCS1, SOCS3
STAT4-Induced​
FCGR1A, IFNG, IRF1, MYC
STAT5-Induced​
BCL2L1 (BCLXL), BCL2L1 (BCLXL), BCL2L1 (BCLXL), CCND1, CDKN1A (p21CIP1, WAF1), IL2RA (CD25), IRF1, OSM
STAT6-Induced​
FCER2, GATA3, IL4, IL4R (CD124)
STAT1 / STAT2 / p48 Induced​
ISG15, OAS1
Apoptosis
AKT1, BCL2L1 (BCLXL), BCL2L1 (BCLXL), BCL2L1 (BCLXL), CDKN1A (p21CIP1, WAF1), F2 (Thrombin), F2R (PAR1), FAS, IL2RA (CD25), MCL1, NFKB1, PRLR, STAT1
Cell Growth and / or Maintenance
Cell Cycle​
CCND1, CDKN1A (p21CIP1, WAF1), EGFR (ERBB1), F2 (Thrombin), F2R (PAR1), IL2RA (CD25), IRF1, JAK2, MYC, STAT1
Cell Growth​
A2M, EGFR (ERBB1), GHR, IFNG, IL4, INSR, OSM, SOCS1, SOCS2, SOCS3, SOCS4, SOCS5
Cell Proliferation​
CSF1R, IL2RG, IL4, MPL, OSM, PDGFRA, SMAD3 (MADH3)
Cell Differentiation​
IL20, IL4, NOS2 (iNOS), SOCS2, SOCS5
Immune Response
Acute-Phase Response​
CEBPB, CRP, F2 (Thrombin), STAT3
Humoral Immune Response​
CSF1R, FCER2, IL4, NFKB1, YY1
Inflammatory Response​
CEBPB, CRP, CXCL9 (MIG), IL20, NFKB1, NOS2 (iNOS), NR3C1 (GRL)
Other Immune Response Genes​
CXCL9 (MIG), FAS, FCGR1A, IFNG, IL2RA (CD25), IL2RG, IL4R (CD124), IL6ST (GP130), IRF1, IRF9, ISG15, OAS1, OSM, PRLR, PTPN11, STUB1
Gene Resource List
Array Layout for PCR Plates
File Size: 153.05 KBLanguage: English
Array Layout for Rotor-Gene Q
File Size: 153.2 KBLanguage: English

Resources

Kit Handbooks (1)
QuantiNova LNA Probe PCR Handbook
Quick-Start Protocols (1)
Certificates of Analysis (1)
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