PRSS22 Gene Summary [Human]
This gene encodes a member of the trypsin family of serine proteases. The enzyme is expressed in the airways in a developmentally regulated manner. The gene is part of a cluster of serine protease genes on chromosome 16. [provided by RefSeq, Jul 2008]
Details
| Type | Protein Coding |
| Official Symbol | PRSS22 |
| Official Name | serine protease 22 [Source:HGNC Symbol;Acc:HGNC:14368] |
| Ensembl ID | ENSG00000005001 |
| Bio databases IDs | |
| Aliases | serine protease 22, brain-specific serine protease 4 |
| Synonyms | 4733401N09Rik, BSSP-4, hBSSP-4, serine protease 22, SP001LA, Tryptase ε |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human PRSS22 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Trypsin-like serine protease
- trypsin
- Tryp_SPc
- serine endopeptidase
- peptidase
- Domain of unknown function (DUF1986)
- protein binding
- protease activator
Pathways
Biological processes and signaling networks where the PRSS22 gene in human plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human PRSS22 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- proteolysis
- positive regulation of peptidase activity
Cellular Component
Where in the cell the gene product is active
- extracellular space
Molecular Function
What the gene product does at the molecular level
- peptidase activator activity
- serine-type endopeptidase activity