Prss22 Gene Summary [Mouse]
Predicted to enable peptidase activator activity and serine-type endopeptidase activity. Predicted to be involved in positive regulation of peptidase activity and proteolysis. Predicted to be located in extracellular space. Is expressed in brain; eye; lung; reproductive system; and stomach. Orthologous to human PRSS22 (serine protease 22). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Prss22 |
| Official Name | protease, serine 22 [Source:MGI Symbol;Acc:MGI:1918085] |
| Ensembl ID | ENSMUSG00000045027 |
| Bio databases IDs | |
| Aliases | protease, serine 22 |
| Synonyms | 4733401N09Rik, BSSP-4, hBSSP-4, serine protease 22, SP001LA, Tryptase ε |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Prss22 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Trypsin-like serine protease
- trypsin
- Tryp_SPc
- serine endopeptidase
- peptidase
- Domain of unknown function (DUF1986)
- protein binding
- protease activator
Pathways
Biological processes and signaling networks where the Prss22 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Prss22 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- proteolysis
- positive regulation of peptidase activity
Cellular Component
Where in the cell the gene product is active
- extracellular space
Molecular Function
What the gene product does at the molecular level
- peptidase activator activity
- serine-type endopeptidase activity