QPCTL Gene Summary [Human]
Enables glutaminyl-peptide cyclotransferase activity and zinc ion binding activity. Acts upstream of or within peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase. Located in Golgi apparatus. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | QPCTL |
| Official Name | glutaminyl-peptide cyclotransferase like [Source:HGNC Symbol;Acc:HGNC:25952] |
| Ensembl ID | ENSG00000011478 |
| Bio databases IDs | |
| Aliases | glutaminyl-peptide cyclotransferase like, glutaminyl cyclase-like |
| Synonyms | 1810019P04Rik, glutaminyl-peptide cyclotransferase-like, gQC, RGD1308128 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human QPCTL often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- glutaminyl-peptide cyclotransferase
- Zinc peptidases M18, M20, M28, and M42
- zinc ion binding
- enzyme
- protein binding
- Peptidase family M28
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Golgi Apparatus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human QPCTL gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase
Cellular Component
Where in the cell the gene product is active
- membrane
- Golgi membrane
- Golgi apparatus
Molecular Function
What the gene product does at the molecular level
- zinc ion binding
- glutaminyl-peptide cyclotransferase activity