CDK17 Gene Summary [Human]

The protein encoded by this gene belongs to the cdc2/cdkx subfamily of the ser/thr family of protein kinases. It has similarity to a rat protein that is thought to play a role in terminally differentiated neurons. Alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq, Jul 2010]

Details

Type
Protein Coding
Official Symbol
CDK17
Official Name
cyclin dependent kinase 17 [Source:HGNC Symbol;Acc:HGNC:8750]
Ensembl ID
ENSG00000059758
Bio databases IDs NCBI: 5128 Ensembl: ENSG00000059758
Aliases cyclin dependent kinase 17
Synonyms 6430598J10Rik, cyclin-dependent kinase 17, PCTAIRE2, PCTK2
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human CDK17 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • kinase
  • Serine/Threonine protein kinases, catalytic domain
  • protein serine/threonine kinase
  • Protein kinase (unclassified specificity)
  • protein kinase
  • Protein Kinases, catalytic domain
  • Protein tyrosine and serine/threonine kinase
  • protein binding
  • Protein kinase domain
  • Tyrosine kinase, catalytic domain

Pathways

Biological processes and signaling networks where the CDK17 gene in human plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • Hutchinson-Gilford progeria syndrome
  • habitual abortion
regulated by
regulates
role in cell
  • phosphorylation in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human CDK17 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • regulation of cell cycle
  • protein phosphorylation

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • cytoplasm

Molecular Function

What the gene product does at the molecular level
  • ATP binding
  • protein binding
  • protein kinase activity
  • cyclin-dependent protein kinase activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.