RBMS2 Gene Summary [Human]
The protein encoded by this gene is a member of a small family of proteins which bind single stranded DNA/RNA. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. The RBMS proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. This protein was isolated by phenotypic complementation of cdc2 and cdc13 mutants of yeast and is thought to suppress cdc2 and cdc13 mutants through the induction of translation of cdc2. [provided by RefSeq, Jul 2008]
Details
| Type | Protein Coding |
| Official Symbol | RBMS2 |
| Official Name | RNA binding motif single stranded interacting protein 2 [Source:HGNC Symbol;Acc:HGNC:9909] |
| Ensembl ID | ENSG00000076067 |
| Bio databases IDs | |
| Aliases | RNA binding motif single stranded interacting protein 2 |
| Synonyms | 2610315E04Rik, RNA binding motif single stranded interacting protein 2, RNA binding motif, single stranded interacting protein 2, SCR3 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human RBMS2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- RNA recognition motif (RRM) superfamily
- RNA recognition motif
- RNA binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human RBMS2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- RNA processing
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytosol
Molecular Function
What the gene product does at the molecular level
- RNA binding
- poly(A) RNA binding
- poly(U) RNA binding
- mRNA 3'-UTR binding