TNRC6C Gene Summary [Human]
Predicted to enable RNA binding activity. Involved in gene silencing by miRNA; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; and positive regulation of nuclear-transcribed mRNA poly(A) tail shortening. Predicted to be located in cytosol. Predicted to be active in P-body and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | TNRC6C |
| Official Name | trinucleotide repeat containing adaptor 6C [Source:HGNC Symbol;Acc:HGNC:29318] |
| Ensembl ID | ENSG00000078687 |
| Bio databases IDs | |
| Aliases | trinucleotide repeat containing adaptor 6C |
| Synonyms | 9930033H14Rik, LOC107985010, mKIAA1582, RGD1310027, trinucleotide repeat containing 6C, trinucleotide repeat containing adaptor 6C |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human TNRC6C often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- UBA domain-like superfamily
- RNA recognition motif (RRM) superfamily
- M domain of GW182
- RNA recognition motif
- TNRC6-PABC binding domain
- protein binding
- Argonaute hook
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Nucleus
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human TNRC6C gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of translation involved in gene silencing by miRNA
- positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
- gene silencing by miRNA
- positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
Cellular Component
Where in the cell the gene product is active
- cytoplasmic mRNA processing body
- cytosol
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- RNA binding