MXRA5 Gene Summary [Human]
This gene encodes one of the matrix-remodelling associated proteins. This protein contains 7 leucine-rich repeats and 12 immunoglobulin-like C2-type domains related to perlecan. This gene has a pseudogene on chromosome Y. [provided by RefSeq, Mar 2010]
Details
| Type | Protein Coding |
| Official Symbol | MXRA5 |
| Official Name | matrix remodeling associated 5 [Source:HGNC Symbol;Acc:HGNC:7539] |
| Ensembl ID | ENSG00000101825 |
| Bio databases IDs | |
| Aliases | matrix remodeling associated 5, adlican |
| Synonyms | matrix remodeling associated 5 |
| Species | Human, Homo sapiens |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human MXRA5 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein phosphatase 1 regulatory subunit 42
- immunoglobulin domain
- Immunoglobulin like
- Immunoglobulin I-set domain
- Leucine rich repeat
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- prostate cancer
- preeclampsia
- organismal death
- breast cancer
- primary pulmonary hypertension
- hemangioma
- angiomatosis
- prostatic intraepithelial neoplasm
- prostatic intraepithelial neoplasia
- HER2 negative hormone receptor negative breast cancer
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human MXRA5 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- response to transforming growth factor beta stimulus
Cellular Component
Where in the cell the gene product is active
- extracellular vesicular exosome
- extracellular region
Molecular Function
What the gene product does at the molecular level
- extracellular matrix structural constituent