RALGPS2 Gene Summary [Human]
Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in regulation of Ral protein signal transduction; regulation of catalytic activity; and small GTPase mediated signal transduction. Predicted to be located in cytoplasm and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Retained Intron |
| Official Symbol | RALGPS2 |
| Official Name | Ral GEF with PH domain and SH3 binding motif 2 [Source:HGNC Symbol;Acc:HGNC:30279] |
| Ensembl ID | ENSG00000116191 |
| Bio databases IDs | |
| Aliases | Ral GEF with PH domain and SH3 binding motif 2 |
| Synonyms | 1810020P17Rik, 2210408F11RIK, 4921528G01Rik, 9130014M22Rik, dJ595C2.1, FLJ25604, Ral GEF with PH domain and SH3 binding motif 2 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human RALGPS2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- PH domain
- protein binding
- RasGEF
- Pleckstrin homology-like domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human RALGPS2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- Ras protein signal transduction
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- guanyl-nucleotide exchange factor activity