MAP7D3 Gene Summary [Human]
The protein encoded by this gene belongs to the MAP7 (microtubule-associated protein 7) family. Alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq, Mar 2010]
Details
| Type | Protein Coding |
| Official Symbol | MAP7D3 |
| Official Name | MAP7 domain containing 3 [Source:HGNC Symbol;Acc:HGNC:25742] |
| Ensembl ID | ENSG00000129680 |
| Bio databases IDs | |
| Aliases | MAP7 domain containing 3 |
| Synonyms | 4933424A10Rik, MAP7 domain containing 3, MDP3, Mtap7d3, RGD1565514 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human MAP7D3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- microtubule binding
- Nuf2, DHR10-like domain
- MAP7 (E-MAP-115) family
- tubulin binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- neoplasia
- metastasis
- organismal death
- coronary artery disease
- Alzheimer disease
role in cell
- expression in
- proliferation
- migration
- invasion by
- organization
- docetaxel sensitivity
- gemcitabine sensitivity
- polymerization
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human MAP7D3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- microtubule polymerization
- microtubule cytoskeleton organization
Cellular Component
Where in the cell the gene product is active
- microtubule cytoskeleton
- cytoplasm
- membrane
- spindle
Molecular Function
What the gene product does at the molecular level
- tubulin binding
- microtubule binding