Map7d3 Gene Summary [Mouse]
Predicted to enable microtubule binding activity. Predicted to be involved in microtubule polymerization. Predicted to be located in cytoplasm and spindle. Predicted to be active in microtubule cytoskeleton. Orthologous to human MAP7D3 (MAP7 domain containing 3). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Map7d3 |
| Official Name | MAP7 domain containing 3 [Source:MGI Symbol;Acc:MGI:2445051] |
| Ensembl ID | ENSMUSG00000067878 |
| Bio databases IDs | |
| Aliases | MAP7 domain containing 3 |
| Synonyms | 4933424A10Rik, MAP7 domain containing 3, MDP3, Mtap7d3, RGD1565514 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Map7d3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- microtubule binding
- Nuf2, DHR10-like domain
- MAP7 (E-MAP-115) family
- tubulin binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- neoplasia
- metastasis
- organismal death
- coronary artery disease
- Alzheimer disease
role in cell
- expression in
- proliferation
- migration
- invasion by
- organization
- docetaxel sensitivity
- gemcitabine sensitivity
- polymerization
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Map7d3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- microtubule polymerization
- microtubule cytoskeleton organization
Cellular Component
Where in the cell the gene product is active
- microtubule cytoskeleton
- cytoplasm
- membrane
- spindle
Molecular Function
What the gene product does at the molecular level
- tubulin binding
- microtubule binding