NIBAN1 Gene Summary [Human]
This gene encodes a member of the family with sequence similarity 129 protein family. This gene is highly expressed in several cancer cells and may serve as a prognostic marker for certain cancers. The encoded protein may play a role in regulating p53-mediated apoptosis. [provided by RefSeq, Sep 2016]
Details
| Type | Protein Coding |
| Official Symbol | NIBAN1 |
| Official Name | niban apoptosis regulator 1 [Source:HGNC Symbol;Acc:HGNC:16784] |
| Ensembl ID | ENSG00000135842 |
| Bio databases IDs | |
| Aliases | niban apoptosis regulator 1, cell growth inhibiting protein 39 |
| Synonyms | AU019833, C1orf24, FAM129A, GIG39, NIBAN, niban apoptosis regulator 1 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human NIBAN1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- cancer
- Epstein-Barr virus infection
- cough
- endometriosis
- lymphomagenesis
- hematologic cancer
- lymphoid cancer
- hematological neoplasia
- lymphatic neoplasia
- colorectal cancer
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Plasma Membrane
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human NIBAN1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of translation
- negative regulation of protein phosphorylation
- positive regulation of protein phosphorylation
- response to endoplasmic reticulum stress
Cellular Component
Where in the cell the gene product is active
- extracellular vesicular exosome
- cytoplasm
- membrane
- cytosol
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding