PHF11 Gene Summary [Human]

This gene encodes a protein containing a PHD (plant homeodomain) type zinc finger. This gene has been identified in some studies as a candidate gene for asthma. Naturally-occurring readthrough transcription may occur from the upstream SETDB2 (SET domain bifurcated 2) gene to this locus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]

Details

Type
Retained Intron
Official Symbol
PHF11
Official Name
PHD finger protein 11 [Source:HGNC Symbol;Acc:HGNC:17024]
Ensembl ID
ENSG00000136147
Bio databases IDs NCBI: 51131 Ensembl: ENSG00000136147
Aliases PHD finger protein 11, IgE responsiveness (atopic)
Synonyms APY, BCAP, IGEL, IGER, IGHER, LOC100362408, MGC 10254, NY-REN-34, PHD finger protein 11, Phf11a
Species
Human, Homo sapiens
OrthologiesRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human PHF11 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • PHD-like zinc-binding domain
  • PHD finger superfamily
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • mumps
  • cardiac hypertrophy
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • nucleoplasm
  • nuclear envelope

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human PHF11 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • nuclear membrane
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • metal ion binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.