ARHGAP20 Gene Summary [Human]
The protein encoded by this gene is an activator of RHO-type GTPases, transducing a signal from RAP1 to RHO and impacting neurite outgrowth. [provided by RefSeq, Sep 2016]
Details
| Type | Protein Coding |
| Official Symbol | ARHGAP20 |
| Official Name | Rho GTPase activating protein 20 [Source:HGNC Symbol;Acc:HGNC:18357] |
| Ensembl ID | ENSG00000137727 |
| Bio databases IDs | |
| Aliases | Rho GTPase activating protein 20 |
| Synonyms | 6530403F17Rik, A530023E23Rik, Kiaa1391, mKIAA1391, RARHOGAP, Rho GTPase activating protein 20 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ARHGAP20 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- RhoGAP domain
- Ubl1_cv_Nsp3_N-like
- enzyme binding
- GTPase activator
- Pleckstrin homology-like domain
- GTPase-activator protein for Rho-like GTPases
- RhoGAP
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human ARHGAP20 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of Rho protein signal transduction
- signal transduction
- regulation of small GTPase mediated signal transduction
Cellular Component
Where in the cell the gene product is active
- cytosol
Molecular Function
What the gene product does at the molecular level
- GTPase activator activity