POGK Gene Summary [Human]
The exact function of the protein encoded by this gene is not known. However, this gene product contains a KRAB domain (which is involved in protein-protein interactions) at the N-terminus, and a transposase domain at the C-terminus, suggesting that it may belong to the family of DNA-mediated transposons in human. [provided by RefSeq, Jul 2008]
Details
| Type | Protein Coding |
| Official Symbol | POGK |
| Official Name | pogo transposable element derived with KRAB domain [Source:HGNC Symbol;Acc:HGNC:18800] |
| Ensembl ID | ENSG00000143157 |
| Bio databases IDs | |
| Aliases | pogo transposable element derived with KRAB domain, KRAB box domain containing 2 |
| Synonyms | 9130401E23Rik, BASS2, KRBOX2, LST003, mKIAA1513, pogo transposable element derived with KRAB domain, pogo transposable element with KRAB domain |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human POGK often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- krueppel associated box
- DDE superfamily endonuclease
- Tc5 transposase DNA-binding domain
- Brinker DNA-binding domain
- protein binding
- KRAB (Kruppel-associated box) domain -A box
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human POGK gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of transcription, DNA-dependent
Cellular Component
Where in the cell the gene product is active
- nucleus
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- DNA binding
- protein binding