Details

Type
Protein Coding
Official Symbol
PLEKHA6
Official Name
pleckstrin homology domain containing A6 [Source:HGNC Symbol;Acc:HGNC:17053]
Ensembl ID
ENSG00000143850
Bio databases IDs NCBI: 22874 Ensembl: ENSG00000143850
Aliases pleckstrin homology domain containing A6
Synonyms 9530028L01RIK, LOC100910093, LOC103690089, P3PBP3, PEPP-3, pleckstrin homology domain containing A6, pleckstrin homology domain containing, family A member 6, RGD1564395
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human PLEKHA6 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Domain with 2 conserved Trp (W) residues
  • WW
  • PH domain
  • protein binding
  • Pleckstrin homology-like domain
  • WW domain

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • papillary renal cell carcinoma
  • papillary renal cell neoplasia
  • renal cell cancer
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human PLEKHA6 gene, providing context for its role in the cell.

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.