ZC3H12C Gene Summary [Human]
Predicted to enable endoribonuclease activity and mRNA binding activity. Predicted to be involved in RNA phosphodiester bond hydrolysis, endonucleolytic. Predicted to be active in cytoplasmic ribonucleoprotein granule and nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | ZC3H12C |
| Official Name | zinc finger CCCH-type containing 12C [Source:HGNC Symbol;Acc:HGNC:29362] |
| Ensembl ID | ENSG00000149289 |
| Bio databases IDs | |
| Aliases | zinc finger CCCH-type containing 12C, MCP induced protein 3 |
| Synonyms | A230108E06, Ai642677, C230027N18Rik, MCPIP3, mKIAA1726, Regnase-3, RGD1565078, zinc finger CCCH-type containing 12C |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ZC3H12C often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- RNA-binding, Nab2-type zinc finger
- Endoribonuclease Regnase 1/ ZC3H12 C-terminal domain
- UBA-like domain
- protein binding
- Zc3h12a-like Ribonuclease NYN domain
- PIN (PilT N terminus) domain: Superfamily
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- acute myeloid leukemia with 11q23 abnormality
- imiquimod-induced psoriasis
- psoriasis
- early missed abortion
role in cell
- number
- expression in
- production in
- upregulation in
- frequency
- degradation in
- downregulation in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human ZC3H12C gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- nucleus
Molecular Function
What the gene product does at the molecular level
- protein binding
- metal ion binding
- mRNA binding
- endoribonuclease activity