SLC37A3 Gene Summary [Human]

Predicted to enable transmembrane transporter activity. Predicted to be involved in carbohydrate transport and transmembrane transport. Is integral component of endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Nonsense Mediated Decay
Official Symbol
SLC37A3
Official Name
solute carrier family 37 member 3 [Source:HGNC Symbol;Acc:HGNC:20651]
Ensembl ID
ENSG00000157800
Bio databases IDs NCBI: 84255 Ensembl: ENSG00000157800
Aliases solute carrier family 37 member 3
Synonyms 2610507O21Rik, LOC100127997, solute carrier family 37 (glycerol-3-phosphate transporter), member 3, solute carrier family 37 member 3, solute carrier family 37, member 3, SPX3, Tsap7
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human SLC37A3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • phosphoglycerate transporter family protein
  • benzoate transport
  • xenobiotic transporter
  • Major Facilitator Superfamily
  • protein binding
  • transporter
  • D-galactonate transporter

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • non-small cell lung cancer
  • non-small cell lung carcinoma
  • Ménière disease
  • male pattern hair loss
  • COVID-19
  • necrotizing enterocolitis
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • endoplasmic reticulum membrane
  • lysosome membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human SLC37A3 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • drug transmembrane transport
  • glucose-6-phosphate transport
  • phosphate ion transmembrane transport

Cellular Component

Where in the cell the gene product is active
  • endoplasmic reticulum membrane
  • lysosomal membrane

Molecular Function

What the gene product does at the molecular level
  • xenobiotic transporter activity
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.