EMSY Gene Summary [Human]
Predicted to enable identical protein binding activity. Predicted to be involved in DNA repair; chromatin organization; and regulation of transcription, DNA-templated. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Retained Intron |
| Official Symbol | EMSY |
| Official Name | EMSY transcriptional repressor, BRCA2 interacting [Source:HGNC Symbol;Acc:HGNC:18071] |
| Ensembl ID | ENSG00000158636 |
| Bio databases IDs | |
| Aliases | EMSY transcriptional repressor, BRCA2 interacting |
| Synonyms | 2210018M11Rik, 2310016L09Rik, AU019521, AU019557, C11orf30, EMSY, BRCA2-interacting transcriptional repressor, EMSY transcriptional repressor, BRCA2 interacting, GL002, RGD1310712 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human EMSY often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- ENT domain
- protein binding
- identical protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- epithelial cancer
- neoplasia
- prostatic carcinoma
- prostate cancer
- clear-cell ovarian carcinoma
- clear cell ovarian cancer
- non-insulin-dependent diabetes mellitus
- schizophrenia
- asthma
- eosinophilic esophagitis
role in cell
- phosphorylation in
- expression in
- cell viability
- accumulation in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human EMSY gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- DNA repair
- regulation of transcription, DNA-dependent
- chromatin organization
Cellular Component
Where in the cell the gene product is active
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- identical protein binding
- protein binding