ABCF3 Gene Summary [Human]
This gene encodes a member of the ATP-binding cassette (ABC) transporter superfamily. ATP-binding cassette proteins transport various molecules across extra- and intracellular membranes. The protein encoded by this gene displays antiviral effect against flaviviruses. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2017]
Details
| Type | Protein Coding |
| Official Symbol | ABCF3 |
| Official Name | ATP binding cassette subfamily F member 3 [Source:HGNC Symbol;Acc:HGNC:72] |
| Ensembl ID | ENSG00000161204 |
| Bio databases IDs | |
| Aliases | ATP binding cassette subfamily F member 3 |
| Synonyms | ATP binding cassette subfamily F member 3, ATP-binding cassette, sub-family F member 3, BB119416, EST201864, FLJ11198 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ABCF3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- FeS assembly ATPase SufC
- proposed F420-0 ABC transporter, ATP-binding protein
- AAA domain, putative AbiEii toxin, Type IV TA system
- protein binding
- urea ABC transporter, ATP-binding protein UrtE
- heme ABC exporter, ATP-binding protein CcmA
- ATP-binding cassette protein, ChvD family
- methyl coenzyme M reductase system, component A2
- phosphonate C-P lyase system protein PhnL
- nickel import ATP-binding protein NikE
- ABC transporter
- thiamine ABC transporter, ATP-binding protein
- P-loop containing Nucleoside Triphosphate Hydrolases
- transporter
- ATPases associated with a variety of cellular activities
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human ABCF3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- defense response to virus
Cellular Component
Where in the cell the gene product is active
- membrane
Molecular Function
What the gene product does at the molecular level
- ATPase activity
- ATP binding
- protein binding
- cadherin binding