ZSWIM2 Gene Summary [Human]
Predicted to enable ubiquitin-protein transferase activity. Predicted to be involved in apoptotic process and protein polyubiquitination. Predicted to act upstream of or within positive regulation of extrinsic apoptotic signaling pathway via death domain receptors. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | ZSWIM2 |
| Official Name | zinc finger SWIM-type containing 2 [Source:HGNC Symbol;Acc:HGNC:30990] |
| Ensembl ID | ENSG00000163012 |
| Bio databases IDs | |
| Aliases | zinc finger SWIM-type containing 2 |
| Synonyms | 1700025P14RIK, 4933437F18Rik, MEX, zinc finger SWIM-type containing 2, zinc finger, SWIM-type containing 2, ZZZ2 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ZSWIM2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- ZZ
- RING finger (Really Interesting New Gene) domain and U-box domain superfamily
- Ring finger
- ubiquitin protein ligase activity
- ubiquitin-protein transferase activity
- SWIM zinc finger
- enzyme
- Ring finger domain
- protein binding
- RING-like zinc finger
- Zinc finger, C3HC4 type (RING finger)
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human ZSWIM2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein polyubiquitination
- apoptotic process
Molecular Function
What the gene product does at the molecular level
- zinc ion binding