BAALC Gene Summary [Human]

This gene was identified by gene expression studies in patients with acute myeloid leukemia (AML). The gene is conserved among mammals and is not found in lower organisms. Tissues that express this gene develop from the neuroectoderm. Multiple alternatively spliced transcript variants that encode different proteins have been described for this gene; however, some of the transcript variants are found only in AML cell lines. [provided by RefSeq, Jul 2008]

Details

Type
Protein Coding
Official Symbol
BAALC
Official Name
BAALC binder of MAP3K1 and KLF4 [Source:HGNC Symbol;Acc:HGNC:14333]
Ensembl ID
ENSG00000164929
Bio databases IDs NCBI: 79870 Ensembl: ENSG00000164929
Aliases BAALC binder of MAP3K1 and KLF4, BAALC, MEKK1 and KLF4 binding
Synonyms 2810457D07Rik, AC164883.1, BAALC binder of MAP3K1 and KLF4, brain and acute leukaemia, cytoplasmic, brain and acute leukemia, cytoplasmic
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human BAALC often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein binding
  • BAALC N-terminus

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • late-onset Alzheimer disease
  • survival
  • myopia
  • disease-free survival
regulated by
role in cell
  • apoptosis
  • expression in
  • proliferation
  • invasion by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • cytosol
  • sarcoplasm
  • nucleoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human BAALC gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • postsynaptic density
  • sarcoplasm
  • cytoplasm
  • membrane raft
  • cytosol
  • neuron projection
  • nucleoplasm

Gene-Specific Assays for Results You Can Trust

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