ZNF503 Gene Summary [Human]
Predicted to enable metal ion binding activity. Involved in G1 to G0 transition involved in cell differentiation; negative regulation of cell population proliferation; and negative regulation of gene expression. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | ZNF503 |
| Official Name | zinc finger protein 503 [Source:HGNC Symbol;Acc:HGNC:23589] |
| Ensembl ID | ENSG00000165655 |
| Bio databases IDs | |
| Aliases | zinc finger protein 503 |
| Synonyms | B830002A16Rik, LOC101929189, MGC2555, Nlz2, NOLZ-1, RP11-399K21.11, Zfp503, zinc finger protein 503, Zpo2 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ZNF503 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- NocA-like zinc-finger protein 1
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- metastasis
- neoplasia
- mammary neoplasm
- hypoplasia
role in cell
- expression in
- migration
- proliferation
- invasion by
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human ZNF503 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of gene expression
- negative regulation of transcription, DNA-dependent
- neural precursor cell proliferation
- negative regulation of cell proliferation
- G1 to G0 transition involved in cell differentiation
Cellular Component
Where in the cell the gene product is active
- nucleus
Molecular Function
What the gene product does at the molecular level
- protein binding
- metal ion binding