Zfp503 Gene Summary [Rat]
Predicted to enable zinc ion binding activity. Predicted to be involved in several processes, including G1 to G0 transition involved in cell differentiation; negative regulation of cell population proliferation; and negative regulation of macromolecule biosynthetic process. Predicted to be active in nucleus. Orthologous to human ZNF503 (zinc finger protein 503). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Zfp503 |
| Official Name | zinc finger protein 503 [Source:RGD Symbol;Acc:1312018] |
| Ensembl ID | ENSRNOG00000014237 |
| Bio databases IDs | |
| Aliases | zinc finger protein 503 |
| Synonyms | B830002A16Rik, LOC101929189, MGC2555, Nlz2, NOLZ-1, RP11-399K21.11, Zfp503, zinc finger protein 503, Zpo2 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Zfp503 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- NocA-like zinc-finger protein 1
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- metastasis
- neoplasia
- mammary neoplasm
- hypoplasia
role in cell
- expression in
- migration
- proliferation
- invasion by
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Zfp503 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of gene expression
- negative regulation of transcription, DNA-dependent
- neural precursor cell proliferation
- negative regulation of cell proliferation
- G1 to G0 transition involved in cell differentiation
Cellular Component
Where in the cell the gene product is active
- nucleus
Molecular Function
What the gene product does at the molecular level
- protein binding
- metal ion binding