NOC3L Gene Summary [Human]
Enables RNA binding activity. Predicted to be involved in DNA replication initiation. Predicted to act upstream of or within fat cell differentiation. Located in mitochondrion; nucleolus; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | NOC3L |
| Official Name | NOC3 like DNA replication regulator [Source:HGNC Symbol;Acc:HGNC:24034] |
| Ensembl ID | ENSG00000173145 |
| Bio databases IDs | |
| Aliases | NOC3 like DNA replication regulator, factor for adipocyte differentiation 24 |
| Synonyms | AD24, C10orf117, FAD24, NOC3-like DNA replication regulator, RGD1560656 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human NOC3L often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Nucleolar complex-associated protein
- CBF/Mak21 family
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Mitochondria
- chromosome
- nucleoplasm
- nucleoli
- nuclear speckles
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human NOC3L gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- DNA-dependent DNA replication initiation
- fat cell differentiation
Cellular Component
Where in the cell the gene product is active
- nuclear speck
- mitochondrion
- nucleolus
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- RNA binding
- chromatin binding