Noc3l Gene Summary [Mouse]

Predicted to enable chromatin binding activity. Acts upstream of or within fat cell differentiation. Located in nuclear speck and nucleolus. Is expressed in several structures, including central nervous system; ganglia; olfactory epithelium; thymus; and urinary system. Orthologous to human NOC3L (NOC3 like DNA replication regulator). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Noc3l
Official Name
NOC3 like DNA replication regulator [Source:MGI Symbol;Acc:MGI:1932610]
Ensembl ID
ENSMUSG00000024999
Bio databases IDs NCBI: 57753 Ensembl: ENSMUSG00000024999
Aliases NOC3 like DNA replication regulator
Synonyms AD24, C10orf117, FAD24, NOC3-like DNA replication regulator, RGD1560656
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Noc3l often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Nucleolar complex-associated protein
  • CBF/Mak21 family

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • lung cancer
  • systemic sclerosis
regulated by
regulates
role in cell
  • proliferation
  • differentiation
  • abnormal number
  • function in
  • processing in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • Mitochondria
  • chromosome
  • nucleoplasm
  • nucleoli
  • nuclear speckles

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Noc3l gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • DNA-dependent DNA replication initiation
  • fat cell differentiation

Cellular Component

Where in the cell the gene product is active
  • nuclear speck
  • mitochondrion
  • nucleolus
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • RNA binding
  • chromatin binding

Gene-Specific Assays for Results You Can Trust

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