GCC1 Gene Summary [Human]
The protein encoded by this gene is a peripheral membrane protein. It is sensitive to brefeldin A. This encoded protein contains a GRIP domain which is thought to be used in targeting. It may play a role in the organization of trans-Golgi network subcompartment involved with membrane transport. [provided by RefSeq, Jul 2008]
Details
| Type | Protein Coding |
| Official Symbol | GCC1 |
| Official Name | GRIP and coiled-coil domain containing 1 [Source:HGNC Symbol;Acc:HGNC:19095] |
| Ensembl ID | ENSG00000179562 |
| Bio databases IDs | |
| Aliases | GRIP and coiled-coil domain containing 1 |
| Synonyms | 4932417P04Rik, GCC1P, GCC88, golgi coiled coil 1, GRIP and coiled-coil domain containing 1 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human GCC1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- golgin-97, RanBP2alpha,Imh1p and p230/golgin-245
- GRIP domain
- enzyme binding
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cellular membrane
- cytosol
- trans Golgi network
- Golgi cisternae
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human GCC1 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- cytosol
- Golgi apparatus
- Golgi membrane
- Golgi trans cisterna
Molecular Function
What the gene product does at the molecular level
- protein binding
- small GTPase binding