ARL14 Gene Summary [Human]
Predicted to enable GTP binding activity. Predicted to be involved in intracellular protein transport and vesicle-mediated transport. Predicted to be located in cytoplasmic vesicle. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | ARL14 |
| Official Name | ADP ribosylation factor like GTPase 14 [Source:HGNC Symbol;Acc:HGNC:22974] |
| Ensembl ID | ENSG00000179674 |
| Bio databases IDs | |
| Aliases | ADP ribosylation factor like GTPase 14 |
| Synonyms | 9130014L17Rik, ADP-ribosylation factor-like 14, ARF7, ARF like GTPase 14, FLJ22595 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ARL14 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Sar1p-like members of the Ras-family of small GTPases
- ADP-ribosylation factor family
- Signal recognition particle receptor beta subunit
- small GTP-binding protein domain
- Ras family
- 50S ribosome-binding GTPase
- protein binding
- Ras of Complex, Roc, domain of DAPkinase
- ADP-ribosylation factor
- P-loop containing Nucleoside Triphosphate Hydrolases
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human ARL14 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- vesicle-mediated transport
- intracellular protein transport
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- cytoplasmic vesicle
Molecular Function
What the gene product does at the molecular level
- GTP binding
- protein binding
- GTPase activity