RPS27L Gene Summary [Human]
This gene encodes a protein sharing 96% amino acid similarity with ribosomal protein S27, which suggests the encoded protein may be a component of the 40S ribosomal subunit. [provided by RefSeq, Jul 2008]
Details
| Type | Processed Transcript |
| Official Symbol | RPS27L |
| Official Name | ribosomal protein S27 like [Source:HGNC Symbol;Acc:HGNC:18476] |
| Ensembl ID | ENSG00000185088 |
| Bio databases IDs | |
| Aliases | ribosomal protein S27 like |
| Synonyms | 1810034D23Rik, ribosomal protein S27-like, Rps27l1 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human RPS27L often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Ribosomal protein S27
- translation activator
- protein binding
- caspase activator
- translation regulator
Pathways
Biological processes and signaling networks where the RPS27L gene in human plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Nucleus
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human RPS27L gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
- positive regulation of translation
- mitotic cell cycle G1/S transition DNA damage checkpoint
- DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis
- activation of cysteine-type endopeptidase activity involved in apoptotic process
- ribosomal small subunit assembly
- translation
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytosolic small ribosomal subunit
Molecular Function
What the gene product does at the molecular level
- RNA binding
- protein binding
- structural constituent of ribosome
- metal ion binding
- translation activator activity
- cysteine-type endopeptidase activator activity involved in apoptotic process