Rps27l Gene Summary [Mouse]
Predicted to enable RNA binding activity; cysteine-type endopeptidase activator activity involved in apoptotic process; and translation activator activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in intracellular signal transduction; positive regulation of translation; and ribosomal small subunit assembly. Predicted to be located in nucleus. Predicted to be part of cytosolic small ribosomal subunit. Is expressed in several structures, including alimentary system; lung; nose; skeletal musculature; and ventricular layer. Orthologous to human RPS27L (ribosomal protein S27 like). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Rps27l |
| Official Name | ribosomal protein S27-like [Source:MGI Symbol;Acc:MGI:1915191] |
| Ensembl ID | ENSMUSG00000036781 |
| Bio databases IDs | |
| Aliases | ribosomal protein S27-like |
| Synonyms | 1810034D23Rik, ribosomal protein S27-like, Rps27l1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rps27l often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Ribosomal protein S27
- translation activator
- protein binding
- caspase activator
- translation regulator
Pathways
Biological processes and signaling networks where the Rps27l gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Nucleus
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Rps27l gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
- positive regulation of translation
- mitotic cell cycle G1/S transition DNA damage checkpoint
- DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis
- activation of cysteine-type endopeptidase activity involved in apoptotic process
- ribosomal small subunit assembly
- translation
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytosolic small ribosomal subunit
Molecular Function
What the gene product does at the molecular level
- RNA binding
- protein binding
- structural constituent of ribosome
- metal ion binding
- translation activator activity
- cysteine-type endopeptidase activator activity involved in apoptotic process