SPATS2L Gene Summary [Human]
Enables RNA binding activity. Located in cytosol; nucleolus; and nucleoplasm. Part of protein-containing complex. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | SPATS2L |
| Official Name | spermatogenesis associated serine rich 2 like [Source:HGNC Symbol;Acc:HGNC:24574] |
| Ensembl ID | ENSG00000196141 |
| Bio databases IDs | |
| Aliases | spermatogenesis associated serine rich 2 like, DNA polymerase transactivated protein 6, stress granule and nucleolar protein |
| Synonyms | 2810022L02RIK, A230104H11Rik, DNAPTP6, LOC100360294, RGD1309930, SGNP, spermatogenesis associated serine rich 2 like, spermatogenesis associated, serine-rich 2-like |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human SPATS2L often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Protein of unknown function (DUF1387)
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- postoperative nausea and vomiting
- non-insulin-dependent diabetes mellitus
- schizophrenia
- atrial fibrillation
- heart failure
- chronic obstructive pulmonary disease
- diabetic nephropathy
- bipolar disorder
- ATAD3A-related type I interferonopathy
- systemic lupus erythematosus
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- cytosol
- nucleoplasm
- nucleoli
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human SPATS2L gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- cytosol
- macromolecular complex
- nucleolus
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- RNA binding