Lrrc10 Gene Summary [Mouse]
Enables actin binding activity and alpha-actinin binding activity. Acts upstream of or within cardiac muscle cell development. Located in several cellular components, including cytoskeleton; mitochondrion; and sarcomere. Is expressed in heart and male reproductive gland or organ. Used to study dilated cardiomyopathy. Orthologous to human LRRC10 (leucine rich repeat containing 10). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Lrrc10 |
| Official Name | leucine rich repeat containing 10 [Source:MGI Symbol;Acc:MGI:2448063] |
| Ensembl ID | ENSMUSG00000060187 |
| Bio databases IDs | |
| Aliases | leucine rich repeat containing 10 |
| Synonyms | D330003I11Rik, HRLRRP, leucine-rich repeat-containing 10, LOC100911101, LRRC10A, Serdin1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Lrrc10 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein phosphatase 1 regulatory subunit 42
- actinin binding
- actin binding
- Leucine rich repeat
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- cytoskeleton
- Mitochondria
- sarcomere
- myofibrils
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Lrrc10 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cardiac muscle cell development
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoskeleton
- mitochondrion
- sarcomere
Molecular Function
What the gene product does at the molecular level
- actin binding
- alpha-actinin binding