DXO Gene Summary [Human]
This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. The function of its protein product is unknown, but its ubiquitous expression and conservation in both simple and complex eukaryotes suggests that this may be a housekeeping gene. [provided by RefSeq, Jul 2008]
Details
| Type | Retained Intron |
| Official Symbol | DXO |
| Official Name | decapping exoribonuclease [Source:HGNC Symbol;Acc:HGNC:2992] |
| Ensembl ID | ENSG00000204348 |
| Bio databases IDs | |
| Aliases | decapping exoribonuclease |
| Synonyms | decapping exoribonuclease, DOM3L, DOM3Z, NG6, RAI1 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human DXO often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- RAI1 like PD-(D/E)XK nuclease
- 5'-3' exonuclease
- pyrophosphatase
- phosphorous-containing acid anhydride hydrolase
- mRNA binding
- enzyme
- protein binding
- magnesium ion binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Plasma Membrane
- cytosol
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human DXO gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- nucleic acid metabolic process
- nuclear-transcribed mRNA catabolic process
- nuclear mRNA surveillance
- RNA destabilization
- mRNA catabolic process
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytosol
- plasma membrane
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- magnesium ion binding
- nucleotide binding
- 5'-3' exonuclease activity
- protein binding
- RNA pyrophosphohydrolase activity
- mRNA binding