DNM3OS Gene Summary [Human]
Predicted to act upstream of or within bone mineralization and skeletal system development. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Long Non-Coding RNA |
| Official Symbol | DNM3OS |
| Official Name | DNM3 opposite strand/antisense RNA [Source:HGNC Symbol;Acc:HGNC:41228] |
| Ensembl ID | ENSG00000230630 |
| Bio databases IDs | |
| Aliases | DNM3 opposite strand/antisense RNA, MIR199A2 host gene (non-protein coding) |
| Synonyms | 6030416H16RIK, DNM3-AS1, DNM3 opposite strand/antisense RNA, dynamin 3, opposite strand, Hag2, LOC100128178, MIR199A2HG, Npn1, P/L01 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human DNM3OS often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- RNA binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- non-insulin-dependent diabetes mellitus
- neoplasia
- esophageal squamous cell carcinoma
- esophageal squamous cell cancer
- autosomal dominant polycystic kidney disease
- nonobstructive azoospermia
- gastric carcinoma
- gastric epithelial cancer
role in cell
- expression in
- molecular cleavage in
- radiosensitivity
- DNA damage response in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human DNM3OS gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cellular response to transforming growth factor beta stimulus
- gene silencing by miRNA
- positive regulation of gene expression
- positive regulation of miRNA catabolic process
Cellular Component
Where in the cell the gene product is active
- RNA-induced silencing complex