EGFL8 Gene Summary [Human]
Predicted to enable signaling receptor binding activity. Predicted to be involved in anatomical structure development. Predicted to act upstream of or within in utero embryonic development. Predicted to be active in cell surface and extracellular region. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | EGFL8 |
| Official Name | EGF like domain multiple 8 [Source:HGNC Symbol;Acc:HGNC:13944] |
| Ensembl ID | ENSG00000239974 |
| Bio databases IDs | |
| Aliases | EGF like domain multiple 8 |
| Synonyms | C6orf8, EGF-like domain 8, EGF like domain multiple 8, EGF-like-domain, multiple 8, NG3, VE-statin 2 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human EGFL8 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- EMI domain
- protein binding
- Coagulation Factor Xa inhibitory site
- EGF_CA
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human EGFL8 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- in utero embryonic development
- anatomical structure development
Cellular Component
Where in the cell the gene product is active
- extracellular region
- cell surface
Molecular Function
What the gene product does at the molecular level
- protein binding
- calcium ion binding
- receptor binding