SPRR2A Gene Summary [Human]
Predicted to be involved in keratinization. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | SPRR2A |
| Official Name | small proline rich protein 2A [Source:HGNC Symbol;Acc:HGNC:11261] |
| Ensembl ID | ENSG00000241794 |
| Bio databases IDs | |
| Aliases | small proline rich protein 2A |
| Synonyms | small proline rich protein 2A, SPR-2A |
| Species | Human, Homo sapiens |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human SPRR2A often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- lipid binding
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cornified envelope
- Extracellular Space
- cytosol
- secretory granules
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human SPRR2A gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- homeostasis of number of cells in a free-living population
- antibacterial humoral response
- defense response to Gram-positive bacterium
Cellular Component
Where in the cell the gene product is active
- cornified envelope
- cytoplasm
- secretory granule
- cytosol
- transport vesicle
- extracellular region
Molecular Function
What the gene product does at the molecular level
- protein binding
- lipid binding