HYPK Gene Summary [Human]
Enables protein N-terminus binding activity. Involved in negative regulation of apoptotic process and protein stabilization. Located in cytoplasm; microtubule cytoskeleton; and nucleoplasm. Part of protein-containing complex. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | HYPK |
| Official Name | huntingtin interacting protein K [Source:HGNC Symbol;Acc:HGNC:18418] |
| Ensembl ID | ENSG00000242028 |
| Bio databases IDs | |
| Aliases | huntingtin interacting protein K, Huntingtin yeast partner K |
| Synonyms | 2310003F16Rik, C15orf63, HSPC136, Huntingtin interacting protein K, RGD1311457 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human HYPK often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- UBA domain-like superfamily
- protein binding
- HYPK UBA domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- microtubule cytoskeleton
- Nucleus
- polysomes
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human HYPK gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of apoptotic process
- protein folding
- protein stabilization
Cellular Component
Where in the cell the gene product is active
- nucleus
- microtubule cytoskeleton
- cytoplasm
- macromolecular complex
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding involved in protein folding
- protein binding