Dgcr2 Gene Summary [Mouse]

Predicted to enable carbohydrate binding activity. Acts upstream of or within response to xenobiotic stimulus. Located in membrane. Is expressed in several structures, including alimentary system; branchial arch; central nervous system; genitourinary system; and limb primordium. Orthologous to human DGCR2 (DiGeorge syndrome critical region gene 2). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Retained Intron
Official Symbol
Dgcr2
Official Name
DiGeorge syndrome critical region gene 2 [Source:MGI Symbol;Acc:MGI:892866]
Ensembl ID
ENSMUSG00000003166
Bio databases IDs NCBI: 13356 Ensembl: ENSMUSG00000003166
Aliases DiGeorge syndrome critical region gene 2
Synonyms 9930034O06Rik, DGS-C, DiGeorge syndrome critical region gene 2, IDD, LAN, LOC100910275, mKIAA0163, SEZ-12
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Dgcr2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • von Willebrand factor type C domain
  • C-type lectin (CTL)/C-type lectin-like (CTLD) domain
  • Lectin C-type domain
  • LDLa
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • schizophrenia
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • cellular membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Dgcr2 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • cognition
  • cell adhesion
  • organ morphogenesis

Cellular Component

Where in the cell the gene product is active
  • membrane

Molecular Function

What the gene product does at the molecular level
  • carbohydrate binding

Gene-Specific Assays for Results You Can Trust

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