Ppp6r3 Gene Summary [Mouse]
Predicted to enable protein phosphatase binding activity and protein phosphatase regulator activity. Predicted to be involved in regulation of signal transduction. Predicted to be located in nucleoplasm and plasma membrane. Predicted to be active in cytosol and nucleus. Is expressed in cerebellum Purkinje cell layer; cerebellum granule cell layer; and neocortex. Orthologous to human PPP6R3 (protein phosphatase 6 regulatory subunit 3). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ppp6r3 |
| Official Name | protein phosphatase 6, regulatory subunit 3 [Source:MGI Symbol;Acc:MGI:1921807] |
| Ensembl ID | ENSMUSG00000024908 |
| Bio databases IDs | |
| Aliases | protein phosphatase 6, regulatory subunit 3 |
| Synonyms | 4930528G08Rik, 9130026N02Rik, C11orf23, D19Bwg1430e, D19Ertd703e, LOC103694577, mKIAA1558, PP6R3, PPCS3, Ppp6r3-ps1, Pptcs3, protein phosphatase 6 regulatory subunit 3, protein phosphatase 6, regulatory subunit 3, Rel. sporulation-induced transcript 4, RGD1307145, SAP190, SAPL, SAPLa, SAPS3, Saps3-ps1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ppp6r3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- SIT4 phosphatase-associated protein
- protein phosphatase binding
- protein phosphatase regulator
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Plasma Membrane
- cytosol
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Ppp6r3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of phosphoprotein phosphatase activity
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytosol
- plasma membrane
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- protein phosphatase binding
- protein phosphatase regulator activity