Brms1l Gene Summary [Mouse]
Predicted to enable histone deacetylase binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of Sin3-type complex. Orthologous to human BRMS1L (BRMS1 like transcriptional repressor). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Brms1l |
| Official Name | breast cancer metastasis-suppressor 1-like [Source:MGI Symbol;Acc:MGI:1196337] |
| Ensembl ID | ENSMUSG00000012076 |
| Bio databases IDs | |
| Aliases | breast cancer metastasis-suppressor 1-like |
| Synonyms | 0710008O11Rik, breast cancer metastasis-suppressor 1-like, BRMS1, BRMS1 like transcriptional repressor, D12Ertd407e, LOC100039915, p40 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Brms1l often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Brms1l gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of transcription from RNA polymerase II promoter
- negative regulation of transforming growth factor beta receptor signaling pathway
- negative regulation of cell migration
Cellular Component
Where in the cell the gene product is active
- nucleus
- Sin3-type complex
Molecular Function
What the gene product does at the molecular level
- protein binding
- histone deacetylase binding