Rps5 Gene Summary [Mouse]
A structural constituent of ribosome. Predicted to be involved in regulation of translational fidelity; ribosomal small subunit assembly; and translation. Part of cytosolic small ribosomal subunit. Is active in synapse. Is expressed in several structures, including brain; embryo ectoderm; genitourinary system; gut; and sensory organ. Orthologous to human RPS5 (ribosomal protein S5). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Rps5 |
| Official Name | ribosomal protein S5 [Source:MGI Symbol;Acc:MGI:1097682] |
| Ensembl ID | ENSMUSG00000012848 |
| Bio databases IDs | |
| Aliases | ribosomal protein S5 |
| Synonyms | 40S ribosomal protein S5, Ribosomal protein s5, S5, uS7 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rps5 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- structural constituent of ribosome
- Ribosomal protein S7
- mRNA binding
- protein binding
Pathways
Biological processes and signaling networks where the Rps5 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- interchromatin granule cluster fractions
- pH resistant lipid raft fraction
- pre-ribosome
- ribosome
- Nucleus
- cytosol
- nucleoplasm
- nucleoli
- nuclear envelope
- synapse
- cytoplasmic fraction
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Rps5 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of translational fidelity
- cytoplasmic translation
- ribosomal small subunit biogenesis
- ribosomal small subunit assembly
- translational initiation
- translation
Cellular Component
Where in the cell the gene product is active
- small-subunit processome
- cytosolic ribosome
- cytosolic small ribosomal subunit
- synapse
- ribosome
- nucleolus
- nucleoplasm
- extracellular vesicular exosome
- focal adhesion
- cytoplasm
- membrane
- cytosol
Molecular Function
What the gene product does at the molecular level
- RNA binding
- protein binding
- structural constituent of ribosome
- mRNA binding
- rRNA binding