Anxa9 Gene Summary [Mouse]
Predicted to enable acetylcholine receptor activity; calcium-dependent phospholipid binding activity; and phosphatidylserine binding activity. Predicted to be involved in cell-cell adhesion. Located in collagen-containing extracellular matrix. Is expressed in several structures, including ganglia; trigeminal nerve; urinary system; vertebral axis musculature; and vibrissa. Orthologous to human ANXA9 (annexin A9). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Anxa9 |
| Official Name | annexin A9 [Source:MGI Symbol;Acc:MGI:1923711] |
| Ensembl ID | ENSMUSG00000015702 |
| Bio databases IDs | |
| Aliases | annexin A9 |
| Synonyms | 1110003P15Rik, 2310069F17Rik, ANNEXIN A9, ANX31, LOC681869 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Anxa9 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- phospholipid binding
- binding protein
- Annexin
- protein binding
- transmembrane receptor
- acetylcholine receptor
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- breast cancer
- neoplasia
- colorectal cancer
- breast carcinoma
- tonsillitis
- pervasive developmental disorder
- neuroblastoma
- neuroblastoma formation
- ductal breast carcinoma
- ductal breast cancer
role in cell
- expression in
- colony formation
- proliferation
- migration
- invasion by
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cell surface
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Anxa9 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- synaptic transmission, cholinergic
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasm
- vesicle membrane
- cytosol
- synapse
- plasma membrane
- cell surface
Molecular Function
What the gene product does at the molecular level
- phosphatidylserine binding
- acetylcholine receptor activity
- protein binding
- calcium ion binding
- phospholipid binding
- calcium-dependent phospholipid binding